Jason Cook (Shawn) & Martha Madison (Belle)
Mark Valley (Jack), Melissa Reeves (Jennifer), Jason Brooks (Peter)
Antony Alda (Johnny) & Lisa Howard (April)
Felecia Bell (Glynnis) & Richard Biggs (Marcus)
Tammy Townsend (Wendy), Thyme Lewis (Jonah), Renee Jones (Lexie)
John Clarke (Mickey) & Suzanne Rogers (Maggie)
Justin Melvey (Colin), Melissa Reeves (Jennifer), Matthew Ashford (Jack)
Peter Reckell (Bo) & Julie Pinson (Billie)
Patricia Huston (Addie) & Robert Knapp (Ben)
Kevin Spirtas (Craig) & Patrika Darbo (Nancy)
Frank Parker (Grandpa Shawn) & Peggy McCay (Caroline)
Jane Elliot (Anjelica) & Joseph Gallison (Neil)
Macdonald Carey (Tom) & Frances Reid (Alice) early and later in their careers as on-screen husband and wife.
Yvonna Kopacz (Wendy) & Thyme Lewis (Jonah)
Melissa Brennan (Jennifer) & Billy Warlock (Frankie)
Paul Logan (Glen) & Tamara Clatterbuck (Barb)
Judi Evans (Adrienne), Wally Kurth (Justin), Jane Elliot (Anjelica)
Robert Kelker-Kelly (Bo) & Lisa Rinna (Billie)
Judi Evans (Bonnie) & John Ingle (Mickey)
Renee Jones (Lexie) & Matt Cedeno (Brandon)
Arleen Sorkin (Calliope) & John de Lancie (Eugene)
Drake Hogestyn (John), Eileen Davidson (Kristen), Thaao Penghlis (Tony)
Thyme Lewis (Jonah) & Lark Voorhies (Wendy)
Arianne Zuker (Nicole) & Bryan Dattilo (Lucas)
Matthew Ashford (Jack) & Melissa Reeves (Jennifer)